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Pharmacology, Biodistribution, and Efficacy of GPCR-Based Pepducins in Disease Models

G protein-coupled receptors (GPCR) are a superfamily of receptors that are vital in a wide array of physiological processes. Modulation of GPCR signaling has been an intensive area of therapeutic study, mainly due to the diverse pathophysiological significance of GPCRs. Pepducins are cell-penetratin...

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Detalhes bibliográficos
Main Authors: Tressel, Sarah L., Koukos, Georgios, Tchernychev, Boris, Jacques, Suzanne L., Covic, Lidija, Kuliopulos, Athan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780409/
https://ncbi.nlm.nih.gov/pubmed/21053136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60761-919-2_19
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