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Interdicting protease-activated receptor-2-driven inflammation with cell-penetrating pepducins
Protease-activated receptor-2 (PAR2), a cell surface receptor for trypsin-like proteases, plays a key role in a number of acute and chronic inflammatory diseases of the joints, lungs, brain, gastrointestinal tract, and vascular systems. Despite considerable effort by the pharmaceutical industry, PAR...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100971/ https://ncbi.nlm.nih.gov/pubmed/21536878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017091108 |
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