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Targeting a Metalloprotease-PAR1 Signaling System with Cell-Penetrating Pepducins Inhibits Angiogenesis, Ascites, and Progression of Ovarian Cancer

Gene chip and proteomic analyses of tumors and stromal tissue has led to the identification of dozens of candidate tumor and host components potentially involved in tumor-stromal interactions, angiogenesis, and progression of invasive disease. In particular, matrix metalloproteases have emerged as i...

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Detalhes bibliográficos
Main Authors: Agarwal, Anika, Covic, Lidija, Sevigny, Leila M, Kaneider, Nicole C, Lazarides, Katherine, Azabdaftari, Gissou, Sharifi, Sheida, Kuliopulos, Athan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735132/
https://ncbi.nlm.nih.gov/pubmed/18790755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0177
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