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Targeting a Metalloprotease-PAR1 Signaling System with Cell-Penetrating Pepducins Inhibits Angiogenesis, Ascites, and Progression of Ovarian Cancer

Gene chip and proteomic analyses of tumors and stromal tissue has led to the identification of dozens of candidate tumor and host components potentially involved in tumor-stromal interactions, angiogenesis, and progression of invasive disease. In particular, matrix metalloproteases have emerged as i...

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Autori principali: Agarwal, Anika, Covic, Lidija, Sevigny, Leila M, Kaneider, Nicole C, Lazarides, Katherine, Azabdaftari, Gissou, Sharifi, Sheida, Kuliopulos, Athan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735132/
https://ncbi.nlm.nih.gov/pubmed/18790755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0177
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