Design, Synthesis and Anti-tuberculosis Activity of 1-Adamantyl-3-heteroaryl Ureas with Improved in vitro Pharmacokinetic Properties

Out of the prominent global ailments, tuberculosis (TB) is still one of the leading causes of death worldwide due to infectious disease. Development of new drugs that shorten the current tuberculosis treatment time and have activity against drug resistant strains is of utmost importance. Towards the...

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Bibliographic Details
Main Authors: North, E. Jeffrey, Scherman, Michael S., Bruhn, David F., Scarborough, Jerrod S., Maddox, Marcus M., Jones, Victoria, Grzegorzewicz, Anna, Yang, Lei, Hess, Tamara, Morisseau, Christophe, Jackson, Mary, McNeil, Michael R., Lee, Richard E.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780361/
https://ncbi.nlm.nih.gov/pubmed/23498915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.02.028
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