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Repeated Nicotine Administration Robustly Increases bPiDDB Inhibitory Potency at α6β2-containing Nicotinic Receptors Mediating Nicotine-evoked Dopamine Release
The novel nicotinic receptor (nAChR) antagonist, N,N’-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), and its chemically-reduced analog, r-bPiDDB, potently inhibit nicotine-evoked dopamine (DA) release from rat striatal slices. Since tobacco smokers self-administer nicotine repeatedly, anima...
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| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3779887/ https://ncbi.nlm.nih.gov/pubmed/20346923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.03.018 |
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