A Physiologically Required G Protein-coupled Receptor (GPCR)-Regulator of G Protein Signaling (RGS) Interaction That Compartmentalizes RGS Activity

G protein-coupled receptors (GPCRs) can interact with regulator of G protein signaling (RGS) proteins. However, the effects of such interactions on signal transduction and their physiological relevance have been largely undetermined. Ligand-bound GPCRs initiate by promoting exchange of GDP for GTP o...

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Autors principals: Croft, Wayne, Hill, Claire, McCann, Eilish, Bond, Michael, Esparza-Franco, Manuel, Bennett, Jeannette, Rand, David, Davey, John, Ladds, Graham
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779728/
https://ncbi.nlm.nih.gov/pubmed/23900842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.497826
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