O-Linked N-Acetylglucosamine Cycling Regulates Mitotic Spindle Organization

Any defects in the correct formation of the mitotic spindle will lead to chromosomal segregation errors, mitotic arrest, or aneuploidy. We demonstrate that O-linked N-acetylglucosamine (O-GlcNAc), a post-translational modification of serine and threonine residues in nuclear and cytoplasmic proteins,...

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Bibliographic Details
Main Authors: Tan, Ee Phie, Caro, Sarah, Potnis, Anish, Lanza, Christopher, Slawson, Chad
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779708/
https://ncbi.nlm.nih.gov/pubmed/23946484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.470187
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