The interdependent, overlapping and differential roles of type I and type II interferons in the pathogenesis of experimental autoimmune encephalomyelitis()

Type I IFNs (IFN-α and IFN-β) and type II IFN (IFN-γ) mediate both regulation and inflammation in multiple sclerosis (MS), neuromyelitis optica (NMO) and in experimental autoimmune encephalomyelitis (EAE). However the underlying mechanism for these Janus-like activities of type I and II IFNs in neur...

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Main Authors: Naves, Rodrigo, Singh, Simer P., Cashman, Kevin S., Rowse, Amber L., Axtell, Robert C., Steinman, Lawrence, Mountz, John D., Steele, Chad, De Sarno, Patrizia, Raman, Chander
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779698/
https://ncbi.nlm.nih.gov/pubmed/23960239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300419
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