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Lithium Controls Central Nervous System Autoimmunity through Modulation of IFN-γ Signaling

Inhibitors of glycogen synthase kinase 3 (GSK3) are being explored as therapy for chronic inflammatory diseases. We previously demonstrated that the GSK inhibitor lithium is beneficial in experimental autoimmune encephalomyelitis (EAE), the mouse model of multiple sclerosis. In this study we report...

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Detalhes bibliográficos
Main Authors: Rowse, Amber L., Naves, Rodrigo, Cashman, Kevin S., McGuire, Donald J., Mbana, Tethia, Raman, Chander, De Sarno, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532311/
https://ncbi.nlm.nih.gov/pubmed/23285134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052658
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