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Type I Interferons: Beneficial in Th1 and Detrimental in Th17 Autoimmunity

In relapsing remitting multiple sclerosis (RRMS), type I interferon (IFN) is considered immuno-modulatory and recombinant forms of IFN-β are the most prescribed treatment for this disease. However, within the RRMS population, 30–50% of MS patients are nonresponsive to this treatment, and it consiste...

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Détails bibliographiques
Publié dans:Clin Rev Allergy Immunol
Auteurs principaux: Axtell, Robert C, Raman, Chander, Steinman, Lawrence
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478162/
https://ncbi.nlm.nih.gov/pubmed/22231516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12016-011-8296-5
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