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The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival

Pigment cells and neuronal cells both are derived from the neural crest. Here, we describe the Pit-Oct-Unc (POU) domain transcription factor Brn3a, normally involved in neuronal development, to be frequently expressed in melanoma, but not in melanocytes and nevi. RNAi-mediated silencing of Brn3a str...

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Detalhes bibliográficos
Main Authors: Hohenauer, Tobias, Berking, Carola, Schmidt, Andreas, Haferkamp, Sebastian, Senft, Daniela, Kammerbauer, Claudia, Fraschka, Sabine, Graf, Saskia Anna, Irmler, Martin, Beckers, Johannes, Flaig, Michael, Aigner, Achim, Höbel, Sabrina, Hoffmann, Franziska, Hermeking, Heiko, Rothenfusser, Simon, Endres, Stefan, Ruzicka, Thomas, Besch, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779452/
https://ncbi.nlm.nih.gov/pubmed/23666755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201862
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