MSX1-Induced Neural Crest-Like Reprogramming Promotes Melanoma Progression

Melanoma cells share many biological properties with neural crest stem cells. Here we show that the homeodomain transcription factor MSX1, which is significantly correlated with melanoma disease progression, reprograms melanocytes and melanoma cells toward a neural crest precursor-like state. MSX1-r...

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Bibliographic Details
Published in:J Invest Dermatol
Main Authors: Heppt, Markus V., Wang, Joshua X., Hristova, Denitsa M., Wei, Zhi, Li, Ling, Evans, Brianna, Beqiri, Marilda, Zaman, Samir, Zhang, Jie, Irmler, Martin, Berking, Carola, Besch, Robert, Beckers, Johannes, Rauscher, Frank J., Sturm, Rick A., Fisher, David E., Herlyn, Meenhard, Fukunaga-Kalabis, Mizuho
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902795/
https://ncbi.nlm.nih.gov/pubmed/28927893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2017.05.038
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