MSX1-Induced Neural Crest-Like Reprogramming Promotes Melanoma Progression

Melanoma cells share many biological properties with neural crest stem cells. Here we show that the homeodomain transcription factor MSX1, which is significantly correlated with melanoma disease progression, reprograms melanocytes and melanoma cells toward a neural crest precursor-like state. MSX1-r...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Heppt, Markus V., Wang, Joshua X., Hristova, Denitsa M., Wei, Zhi, Li, Ling, Evans, Brianna, Beqiri, Marilda, Zaman, Samir, Zhang, Jie, Irmler, Martin, Berking, Carola, Besch, Robert, Beckers, Johannes, Rauscher, Frank J., Sturm, Rick A., Fisher, David E., Herlyn, Meenhard, Fukunaga-Kalabis, Mizuho
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902795/
https://ncbi.nlm.nih.gov/pubmed/28927893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2017.05.038
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