MSX1-Induced Neural Crest-Like Reprogramming Promotes Melanoma Progression

Melanoma cells share many biological properties with neural crest stem cells. Here we show that the homeodomain transcription factor MSX1, which is significantly correlated with melanoma disease progression, reprograms melanocytes and melanoma cells toward a neural crest precursor-like state. MSX1-r...

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Pubblicato in:J Invest Dermatol
Autori principali: Heppt, Markus V., Wang, Joshua X., Hristova, Denitsa M., Wei, Zhi, Li, Ling, Evans, Brianna, Beqiri, Marilda, Zaman, Samir, Zhang, Jie, Irmler, Martin, Berking, Carola, Besch, Robert, Beckers, Johannes, Rauscher, Frank J., Sturm, Rick A., Fisher, David E., Herlyn, Meenhard, Fukunaga-Kalabis, Mizuho
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902795/
https://ncbi.nlm.nih.gov/pubmed/28927893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2017.05.038
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