MSX1-Induced Neural Crest-Like Reprogramming Promotes Melanoma Progression

Melanoma cells share many biological properties with neural crest stem cells. Here we show that the homeodomain transcription factor MSX1, which is significantly correlated with melanoma disease progression, reprograms melanocytes and melanoma cells toward a neural crest precursor-like state. MSX1-r...

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Bibliografski detalji
Izdano u:J Invest Dermatol
Glavni autori: Heppt, Markus V., Wang, Joshua X., Hristova, Denitsa M., Wei, Zhi, Li, Ling, Evans, Brianna, Beqiri, Marilda, Zaman, Samir, Zhang, Jie, Irmler, Martin, Berking, Carola, Besch, Robert, Beckers, Johannes, Rauscher, Frank J., Sturm, Rick A., Fisher, David E., Herlyn, Meenhard, Fukunaga-Kalabis, Mizuho
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902795/
https://ncbi.nlm.nih.gov/pubmed/28927893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2017.05.038
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