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The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival
Pigment cells and neuronal cells both are derived from the neural crest. Here, we describe the Pit-Oct-Unc (POU) domain transcription factor Brn3a, normally involved in neuronal development, to be frequently expressed in melanoma, but not in melanocytes and nevi. RNAi-mediated silencing of Brn3a str...
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
WILEY-VCH Verlag
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3779452/ https://ncbi.nlm.nih.gov/pubmed/23666755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201862 |
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