Posttransplantation Systemic Immunomodulation with SA-FasL–Engineered Donor Splenocytes Has Robust Efficacy in Preventing Cardiac Allograft Rejection in Mice

Apoptosis induced by the engagement of FasL with Fas receptor on the surface of lymphocytes is an important immune homeostatic mechanism that ensures tolerance to self-antigens under normal physiologic conditions. As such, FasL has been extensively tested as a tolerogenic molecule with the use of ge...

Full description

Saved in:

Bibliographic Details
Main Authors:	Zhao, H., Woodward, K. B., Shirwan, H., Grimany-Nuno, O., Yolcu, E. S.
Format:	Artigo
Language:	Inglês
Published:	2013
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3779053/ https://ncbi.nlm.nih.gov/pubmed/23769048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.transproceed.2013.01.049
Tags:	Add Tag No Tags, Be the first to tag this record!

Posttransplantation Systemic Immunomodulation with SA-FasL–Engineered Donor Splenocytes Has Robust Efficacy in Preventing Cardiac Allograft Rejection in Mice

Similar Items