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Induction of Tolerance to Cardiac Allografts Using Donor Splenocytes Engineered to Display on Their Surface an Exogenous FasL Protein

The critical role played by FasL in immune homeostasis renders this molecule as an attractive target for immunomodulation to achieve tolerance to auto and transplantation antigens. Immunomodulation with genetically modified cells expressing FasL was shown to induce tolerance to alloantigens. However...

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Bibliografske podrobnosti
Main Authors: Yolcu, Esma S., Gu, Xiao, Lacelle, Chantale, Zhao, Hong, Bandura-Morgan, Laura, Askenasy, Nadir, Shirwan, Haval
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593473/
https://ncbi.nlm.nih.gov/pubmed/18606644
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