Enzastaurin before and concomitant with radiation therapy, followed by enzastaurin maintenance therapy, in patients with newly diagnosed glioblastoma without MGMT promoter hypermethylation

BACKGROUND: This study's primary objective was evaluation of the progression-free survival rate at 6 months (PFS-6) in patients with newly diagnosed glioblastoma without O(6)-methylguanine-DNA-methyltransferase (MGMT) promoter hypermethylation postsurgically treated with enzastaurin before and...

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Main Authors: Wick, Wolfgang, Steinbach, Joachim P., Platten, Michael, Hartmann, Christian, Wenz, Frederik, von Deimling, Andreas, Shei, Peipei, Moreau-Donnet, Valerie, Stoffregen, Clemens, Combs, Stephanie E.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Clinical Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779043/
https://ncbi.nlm.nih.gov/pubmed/23911595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not100
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