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Prognostic significance of IDH-1 and MGMT in patients with glioblastoma: One step forward, and one step back?

A group of 160 patients with primary glioblastoma treated with radiotherapy and temozolomide was analyzed for the impact of O6-methly-guanly-methyl-transferase (MGMT)-promoter methylation as well as isocitrate dehydrogenase (IDH)1-mutational status. Unexpectedly, overall survival or progression-free...

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Podrobná bibliografie
Hlavní autoři: Combs, Stephanie E, Rieken, Stefan, Wick, Wolfgang, Abdollahi, Amir, von Deimling, Andreas, Debus, Jürgen, Hartmann, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199258/
https://ncbi.nlm.nih.gov/pubmed/21910919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-6-115
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