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Prognostic significance of IDH-1 and MGMT in patients with glioblastoma: One step forward, and one step back?
A group of 160 patients with primary glioblastoma treated with radiotherapy and temozolomide was analyzed for the impact of O6-methly-guanly-methyl-transferase (MGMT)-promoter methylation as well as isocitrate dehydrogenase (IDH)1-mutational status. Unexpectedly, overall survival or progression-free...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3199258/ https://ncbi.nlm.nih.gov/pubmed/21910919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-6-115 |
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