Feasibility of real-time molecular profiling for patients with newly diagnosed glioblastoma without MGMT promoter hypermethylation—the NCT Neuro Master Match (N(2)M(2)) pilot study

BACKGROUND: O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation status is a predictive biomarker in glioblastoma patients. Glioblastoma without hypermethylated MGMT promoter is largely resistant to treatment with temozolomide. These patients are in particular need of new treatment a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Pfaff, Elke, Kessler, Tobias, Balasubramanian, Gnana Prakash, Berberich, Anne, Schrimpf, Daniel, Wick, Antje, Debus, Jürgen, Unterberg, Andreas, Bendszus, Martin, Herold-Mende, Christel, Capper, David, Schenkel, Irini, Eisenmenger, Andreas, Dettmer, Susan, Brors, Benedikt, Platten, Michael, Pfister, Stefan M, von Deimling, Andreas, Jones, David T W, Wick, Wolfgang, Sahm, Felix
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961072/
https://ncbi.nlm.nih.gov/pubmed/29165638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox216
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados