Feasibility of real-time molecular profiling for patients with newly diagnosed glioblastoma without MGMT promoter hypermethylation—the NCT Neuro Master Match (N(2)M(2)) pilot study

BACKGROUND: O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation status is a predictive biomarker in glioblastoma patients. Glioblastoma without hypermethylated MGMT promoter is largely resistant to treatment with temozolomide. These patients are in particular need of new treatment a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Pfaff, Elke, Kessler, Tobias, Balasubramanian, Gnana Prakash, Berberich, Anne, Schrimpf, Daniel, Wick, Antje, Debus, Jürgen, Unterberg, Andreas, Bendszus, Martin, Herold-Mende, Christel, Capper, David, Schenkel, Irini, Eisenmenger, Andreas, Dettmer, Susan, Brors, Benedikt, Platten, Michael, Pfister, Stefan M, von Deimling, Andreas, Jones, David T W, Wick, Wolfgang, Sahm, Felix
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Clinical Investigations
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961072/
https://ncbi.nlm.nih.gov/pubmed/29165638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox216
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg