Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration

Graft-versus-host disease (GVHD) is a critical complication after allogeneic bone marrow transplantation. During GVHD, donor T cells are activated by host antigen-presenting cells and differentiate into T-effector cells (Teffs) that migrate to GVHD target organs. However, local environmental factors...

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מידע ביבליוגרפי
Main Authors: Aoyama, Kazutoshi, Saha, Asim, Tolar, Jakub, Riddle, Megan J., Veenstra, Rachelle G., Taylor, Patricia A., Blomhoff, Rune, Panoskaltsis-Mortari, Angela, Klebanoff, Christopher A., Socié, Gérard, Munn, David H., Murphy, William J., Serody, Jonathan S., Fulton, LeShara M., Teshima, Takanori, Chandraratna, Roshantha A., Dmitrovsky, Ethan, Guo, Yanxia, Noelle, Randolph J., Blazar, Bruce R.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Hematology 2013
נושאים:
Transplantation
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778553/
https://ncbi.nlm.nih.gov/pubmed/23814022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-11-470252
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