A retinoic acid–dependent checkpoint in the development of CD4(+) T cell–mediated immunity

It is known that vitamin A and its metabolite, retinoic acid (RA), are essential for host defense. However, the mechanisms for how RA controls inflammation are incompletely understood. The findings presented in this study show that RA signaling occurs concurrent with the development of inflammation....

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Detalhes bibliográficos
Main Authors: Pino-Lagos, Karina, Guo, Yanxia, Brown, Chrysothemis, Alexander, Matthew P., Elgueta, Raúl, Bennett, Kathryn A., De Vries, Victor, Nowak, Elizabeth, Blomhoff, Rune, Sockanathan, Shanthini, Chandraratna, Roshantha A., Dmitrovsky, Ethan, Noelle, Randolph J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171100/
https://ncbi.nlm.nih.gov/pubmed/21859847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20102358
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