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A retinoic acid–dependent checkpoint in the development of CD4(+) T cell–mediated immunity

It is known that vitamin A and its metabolite, retinoic acid (RA), are essential for host defense. However, the mechanisms for how RA controls inflammation are incompletely understood. The findings presented in this study show that RA signaling occurs concurrent with the development of inflammation....

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Bibliografiske detaljer
Main Authors: Pino-Lagos, Karina, Guo, Yanxia, Brown, Chrysothemis, Alexander, Matthew P., Elgueta, Raúl, Bennett, Kathryn A., De Vries, Victor, Nowak, Elizabeth, Blomhoff, Rune, Sockanathan, Shanthini, Chandraratna, Roshantha A., Dmitrovsky, Ethan, Noelle, Randolph J.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171100/
https://ncbi.nlm.nih.gov/pubmed/21859847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20102358
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