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Snail cooperates with Kras(G12D) to promote pancreatic fibrosis

Patients with pancreatic cancer, which is characterized by an extensive collagen-rich fibrotic reaction, often present with metastases. A critical step in cancer metastasis is epithelial to mesenchymal transition, which can be orchestrated by Snail family of transcription factors. To understand the...

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Hlavní autoři: Shields, Mario A., Ebine, Kazumi, Sahai, Vaibhav, Kumar, Krishan, Siddiqui, Kulsumjehan, Hwang, Rosa F., Grippo, Paul J., Munshi, Hidayatullah G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778055/
https://ncbi.nlm.nih.gov/pubmed/23761168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0637
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