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Crystal Structures of Lgr4 and its complex with R-spondin1
The Leucine-rich repeat-containing, G protein coupled receptors (Lgrs) are a large membrane protein family mediating signaling events during development and in the adult organism. Type 2 Lgrs, including Lgr4, Lgr5 and Lgr6, play crucial roles in embryonic development and in several cancers. They als...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3777832/ https://ncbi.nlm.nih.gov/pubmed/23891289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.07.001 |
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