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Crystal Structures of Lgr4 and its complex with R-spondin1

The Leucine-rich repeat-containing, G protein coupled receptors (Lgrs) are a large membrane protein family mediating signaling events during development and in the adult organism. Type 2 Lgrs, including Lgr4, Lgr5 and Lgr6, play crucial roles in embryonic development and in several cancers. They als...

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Detalhes bibliográficos
Main Authors: Xu, Kai, Xu, Yan, Rajashankar, Kanagalaghatta R., Robev, Dorothea, Nikolov, Dimitar B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777832/
https://ncbi.nlm.nih.gov/pubmed/23891289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.07.001
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