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NMR-assisted computational studies of peptidomimetic inhibitors bound in the hydrophobic pocket of HIV-1 glycoprotein 41
Due to the inherently flexible nature of a protein – protein interaction surface, it is difficult both to inhibit the association with a small molecule, and to predict how it might bind to the surface. In this study, we have examined small molecules that mediate the interaction between a WWI motif o...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3777804/ https://ncbi.nlm.nih.gov/pubmed/23893342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-013-9662-6 |
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