The EF-G-like GTPase Snu114p Regulates Spliceosome Dynamics Mediated by Brr2p, a DExD/H-box ATPase

Binding of a pre-mRNA substrate triggers spliceosome activation while the release of the mRNA product triggers spliceosome disassembly. The mechanisms that underlie the regulation of these rearrangements remain unclear. We find evidence that the GTPase Snu114p mediates the regulation of spliceosome...

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Hauptverfasser: Small, Eliza C., Leggett, Stephanie R., Winans, Adrienne A., Staley, Jonathan P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777414/
https://ncbi.nlm.nih.gov/pubmed/16885028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.05.043
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