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The EF-G-like GTPase Snu114p Regulates Spliceosome Dynamics Mediated by Brr2p, a DExD/H-box ATPase

Binding of a pre-mRNA substrate triggers spliceosome activation while the release of the mRNA product triggers spliceosome disassembly. The mechanisms that underlie the regulation of these rearrangements remain unclear. We find evidence that the GTPase Snu114p mediates the regulation of spliceosome...

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Detalhes bibliográficos
Main Authors: Small, Eliza C., Leggett, Stephanie R., Winans, Adrienne A., Staley, Jonathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777414/
https://ncbi.nlm.nih.gov/pubmed/16885028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.05.043
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