Loading...
Pharmacodynamic modeling of cell cycle and apoptotic effects of gemcitabine on pancreatic adenocarcinoma cells
PURPOSE: The standard of care for treating patients with pancreatic adenocarcinomas includes gemcitabine (2′,2′-difluorodeoxycytidine). Gemcitabine primarily elicits its response by stalling the DNA replication forks of cells in the S phase of the cell cycle. To provide a quantitative framework for...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3777243/ https://ncbi.nlm.nih.gov/pubmed/23835677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-013-2226-6 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|