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Mechanism-based mathematical modeling of combined gemcitabine and birinapant in pancreatic cancer cells
Combination chemotherapy is standard treatment for pancreatic cancer. However, current drugs lack efficacy for most patients and selection and evaluation of new combination regimens is empirical and time-consuming. The efficacy of gemcitabine, a standard-of-care agent, combined with birinapant, a pr...
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| Publicado no: | J Pharmacokinet Pharmacodyn |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4583820/ https://ncbi.nlm.nih.gov/pubmed/26252969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-015-9429-x |
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