Genetic Deficiency of Anti-Aging Gene Klotho Exacerbates Early Nephropathy in STZ-Induced Diabetes in Male Mice

Klotho is a recently discovered anti-aging gene and is primarily expressed in kidneys. In humans, the klotho level decreases with age whereas the prevalence of chronic kidney disease (CKD) increases with age. Diabetic nephropathy is the most common form of CKD, which leads to end-stage renal disease...

Full description

Saved in:
Bibliographic Details
Main Authors: Lin, Yi, Kuro-o, Makoto, Sun, Zhongjie
Format: Artigo
Language:Inglês
Published: Endocrine Society 2013
Subjects:
Renal-Cardiac-Vascular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776873/
https://ncbi.nlm.nih.gov/pubmed/23928372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1053
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items