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A potential link between phosphate and aging – lessons from Klotho-deficient mice

Phosphate homeostasis is maintained primarily by a bone-kidney endocrine axis. When phosphate is in excess, fibroblast growth factor-23 (FGF23) is secreted from bone and acts on kidney to promote phosphate excretion into urine. FGF23 also reduces serum vitamin D levels to suppress phosphate absorpti...

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Bibliografische gegevens
Hoofdauteur: Kuro-o, Makoto
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862786/
https://ncbi.nlm.nih.gov/pubmed/20197072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2010.02.008
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