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Klotho and aging
The klotho gene encodes a single-pass transmembrane protein that forms a complex with multiple fibroblast growth factor (FGF) receptors and functions as an obligatory co-receptor for FGF23, a bone-derived hormone that induces negative phosphate balance. Defects in either Klotho or Fgf23 gene express...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743784/ https://ncbi.nlm.nih.gov/pubmed/19230844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2009.02.005 |
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