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Role of Klotho in Aging, Phosphate Metabolism, and CKD
The klotho gene (KL) was first identified as a putative aging-suppressor gene that extended lifespan when over-expressed, and accelerated aging-like phenotypes when disrupted in mice. It encodes a single-pass transmembrane protein and is expressed predominantly in kidney, where it functions as an ob...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3191324/ https://ncbi.nlm.nih.gov/pubmed/21496980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.ajkd.2010.12.027 |
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