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A potential link between phosphate and aging – lessons from Klotho-deficient mice
Phosphate homeostasis is maintained primarily by a bone-kidney endocrine axis. When phosphate is in excess, fibroblast growth factor-23 (FGF23) is secreted from bone and acts on kidney to promote phosphate excretion into urine. FGF23 also reduces serum vitamin D levels to suppress phosphate absorpti...
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| Natura: | Artigo |
| Lingua: | Inglês |
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2010
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862786/ https://ncbi.nlm.nih.gov/pubmed/20197072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2010.02.008 |
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