Structure-activity relationships of polybiguanides with activity against human immunodeficiency virus type 1

Previous investigations showing that polydisperse biguanide (PDBG) molecules have activity against human immunodeficiency virus type 1 (HIV-1) also suggested a relationship between PDBG biologic activity and the lengths of hydrocarbon linkers surrounding the positively charged biguanide unit. To bet...

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Bibliografiske detaljer
Main Authors: Passic, Shendra R., Ferguson, Mary Lee, Catalone, Bradley J., Kish-Catalone, Tina, Kholodovych, Vladyslav, Zhu, Wei, Welsh, William, Rando, Robert, Howett, Mary K., Wigdahl, Brian, Labib, Mohamed, Krebs, Fred C.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776307/
https://ncbi.nlm.nih.gov/pubmed/21106331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopha.2010.10.001
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