Dysfunction of the mTOR pathway is a risk factor for Alzheimer’s disease

BACKGROUND: The development of disease-modifying therapies for Alzheimer’s disease is hampered by our lack of understanding of the early pathogenic mechanisms and the lack of early biomarkers and risk factors. We have documented the expression pattern of mTOR regulated genes in the frontal cortex of...

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Détails bibliographiques
Auteurs principaux: Yates, Sharon C, Zafar, Amen, Hubbard, Paul, Nagy, Sheila, Durant, Sarah, Bicknell, Roy, Wilcock, Gordon, Christie, Sharon, Esiri, Margaret M, Smith, A David, Nagy, Zsuzsanna
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776211/
https://ncbi.nlm.nih.gov/pubmed/24252508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-3
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