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Activation of mTOR: a culprit of Alzheimer’s disease?
Alzheimer’s disease (AD) is characterized by cognitive impairment in clinical presentation, and by β-amyloid (Aβ) production and the hyper-phosphorylation of tau in basic research. More highlights demonstrate that the activation of the mammalian target of rapamycin (mTOR) enhances Aβ generation and...
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| Publicado no: | Neuropsychiatr Dis Treat |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4399516/ https://ncbi.nlm.nih.gov/pubmed/25914534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S75717 |
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