The Effects of Two Polymorphisms on p21(cip1) Function and Their Association with Alzheimer’s Disease in a Population of European Descent

With the exception of ApoE4, genome-wide association studies have failed to identify strong genetic risk factors for late-onset Alzheimer’s disease, despite strong evidence of heritability, suggesting that many low penetrance genes may be involved. Additionally, the nature of the identified genetic...

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Publicat a:PLoS One
Autors principals: Yates, Sharon C., Zafar, Amen, Rabai, Erzsebet M., Foxall, James B., Nagy, Sheila, Morrison, Karen E., Clarke, Carl, Esiri, Margaret M., Christie, Sharon, Smith, A. David, Nagy, Zsuzsanna
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308198/
https://ncbi.nlm.nih.gov/pubmed/25625488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114050
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