Dysfunction of the mTOR pathway is a risk factor for Alzheimer’s disease

BACKGROUND: The development of disease-modifying therapies for Alzheimer’s disease is hampered by our lack of understanding of the early pathogenic mechanisms and the lack of early biomarkers and risk factors. We have documented the expression pattern of mTOR regulated genes in the frontal cortex of...

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Detalhes bibliográficos
Main Authors: Yates, Sharon C, Zafar, Amen, Hubbard, Paul, Nagy, Sheila, Durant, Sarah, Bicknell, Roy, Wilcock, Gordon, Christie, Sharon, Esiri, Margaret M, Smith, A David, Nagy, Zsuzsanna
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776211/
https://ncbi.nlm.nih.gov/pubmed/24252508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-3
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