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Age- and calorie restriction-related changes in rat brain mitochondrial DNA and TFAM binding

Aging markedly affects mitochondrial biogenesis and functions particularly in tissues highly dependent on the organelle’s bioenergetics capability such as the brain’s frontal cortex. Calorie restriction (CR) diet is, so far, the only intervention able to delay or prevent the onset of several age-rel...

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Autores principales: Picca, Anna, Fracasso, Flavio, Pesce, Vito, Cantatore, Palmiro, Joseph, Anna-Maria, Leeuwenburgh, Christiaan, Gadaleta, Maria Nicola, Lezza, Angela Maria Serena
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Netherlands 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776104/
https://ncbi.nlm.nih.gov/pubmed/22945739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-012-9465-z
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