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Age- and calorie restriction-related changes in rat brain mitochondrial DNA and TFAM binding

Aging markedly affects mitochondrial biogenesis and functions particularly in tissues highly dependent on the organelle’s bioenergetics capability such as the brain’s frontal cortex. Calorie restriction (CR) diet is, so far, the only intervention able to delay or prevent the onset of several age-rel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Picca, Anna, Fracasso, Flavio, Pesce, Vito, Cantatore, Palmiro, Joseph, Anna-Maria, Leeuwenburgh, Christiaan, Gadaleta, Maria Nicola, Lezza, Angela Maria Serena
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776104/
https://ncbi.nlm.nih.gov/pubmed/22945739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-012-9465-z
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