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Age- and calorie restriction-related changes in rat brain mitochondrial DNA and TFAM binding

Aging markedly affects mitochondrial biogenesis and functions particularly in tissues highly dependent on the organelle’s bioenergetics capability such as the brain’s frontal cortex. Calorie restriction (CR) diet is, so far, the only intervention able to delay or prevent the onset of several age-rel...

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Détails bibliographiques
Auteurs principaux: Picca, Anna, Fracasso, Flavio, Pesce, Vito, Cantatore, Palmiro, Joseph, Anna-Maria, Leeuwenburgh, Christiaan, Gadaleta, Maria Nicola, Lezza, Angela Maria Serena
Format: Artigo
Langue:Inglês
Publié: Springer Netherlands 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776104/
https://ncbi.nlm.nih.gov/pubmed/22945739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-012-9465-z
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