KIT receptor gain-of-function in hematopoiesis enhances stem cell self-renewal and promotes progenitor cell expansion

The KIT receptor tyrosine kinase has important roles in hematopoiesis. We have recently produced a mouse model for imatinib resistant gastrointestinal stromal tumor (GIST) carrying the Kit(V558Δ) and Kit(T669I) (human KIT(T670I)) mutations found in imatinib-resistant GIST. The Kit(V558Δ;T669I/+) mic...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Deshpande, Shayu, Bosbach, Benedikt, Yozgat, Yasemin, Park, Christopher Y., Moore, Malcolm A.S., Besmer, Peter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775897/
https://ncbi.nlm.nih.gov/pubmed/23681919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1419
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller