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Hypoxia-inducible C-to-U coding RNA editing downregulates SDHB in monocytes

Background. RNA editing is a post-transcriptional regulatory mechanism that can alter the coding sequences of certain genes in response to physiological demands. We previously identified C-to-U RNA editing (C136U, R46X) which inactivates a small fraction of succinate dehydrogenase (SDH; mitochondria...

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Detalhes bibliográficos
Main Authors: Baysal, Bora E., De Jong, Kitty, Liu, Biao, Wang, Jianmin, Patnaik, Santosh K., Wallace, Paul K., Taggart, Robert T.
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775634/
https://ncbi.nlm.nih.gov/pubmed/24058882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.152
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