Caricamento...
Mitochondrial complex II regulates a distinct oxygen sensing mechanism in monocytes
Mutations in mitochondrial complex II (succinate dehydrogenase; SDH) genes predispose to paraganglioma tumors that show constitutive activation of hypoxia responses. We recently showed that SDHB mRNAs in hypoxic monocytes gain a stop codon mutation by APOBEC3A-mediated C-to-U RNA editing. Here, we t...
Salvato in:
| Pubblicato in: | Hum Mol Genet |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6074833/ https://ncbi.nlm.nih.gov/pubmed/28204537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx041 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|