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APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages
The extent, regulation and enzymatic basis of RNA editing by cytidine deamination are incompletely understood. Here we show that transcripts of hundreds of genes undergo site-specific C>U RNA editing in macrophages during M1 polarization and in monocytes in response to hypoxia and interferons. Th...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Pub. Group
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4411297/ https://ncbi.nlm.nih.gov/pubmed/25898173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7881 |
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