Transient overexpression of exogenous APOBEC3A causes C-to-U RNA editing of thousands of genes

APOBEC3A cytidine deaminase induces site-specific C-to-U RNA editing of hundreds of genes in monocytes exposed to hypoxia and/or interferons and in pro-inflammatory macrophages. To examine the impact of APOBEC3A overexpression, we transiently expressed APOBEC3A in HEK293T cell line and performed RNA...

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Publicado en:RNA Biol
Autores principales: Sharma, Shraddha, Patnaik, Santosh K., Kemer, Zeynep, Baysal, Bora E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2016
Materias:
Brief Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449087/
https://ncbi.nlm.nih.gov/pubmed/27149507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1184387
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