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Transcription factor-driven conversion of quiescent cardiomyocytes to pacemaker cells
The heartbeat originates within the sinoatrial node (SAN), a small highly-specialized structure containing <10,000 genuine pacemaker cells. The ~5 billion working cardiomyocytes downstream of the SAN remain quiescent when it fails, leading to circulatory collapse and fueling a $6B/year electronic...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3775583/ https://ncbi.nlm.nih.gov/pubmed/23242162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2465 |
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