Transcriptional Suppression of Connexin43 by TBX18 Undermines Cell-Cell Electrical Coupling in Postnatal Cardiomyocytes

T-box transcription factors figure prominently in embryonic cardiac cell lineage specifications. Mesenchymal precursor cells expressing Tbx18 give rise to the heart's pacemaker, the sinoatrial node (SAN). We sought to identify targets of TBX18 transcriptional regulation in the heart by forced a...

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Bibliographic Details
Main Authors: Kapoor, Nidhi, Galang, Giselle, Marbán, Eduardo, Cho, Hee Cheol
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077608/
https://ncbi.nlm.nih.gov/pubmed/21205823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.185298
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