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Ligand/kappa-Opioid Receptor Interactions: Insights from the X-Ray Crystal Structure

During the past five years, the three-dimensional structures of 14 different G-protein coupled receptors (GPCRs) have been resolved by X-ray crystallography. The most recently published structures, those of the opioid receptors (ORs), are remarkably important in pain modulation, drug addiction, and...

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Autores principales: Martinez-Mayorga, Karina, Byler, Kendall G., Yongye, Austin B., Giulianotti, Marc A., Dooley, Colette T., Houghten, Richard A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775475/
https://ncbi.nlm.nih.gov/pubmed/23792349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2013.05.021
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